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A. Salek-Haddadi, M. Merschhemke, L. Lemieux, D. R. Fish. Simultaneous EEG-Correlated Ictal fMRI. NeuroImage, 16(1):32-40, 2002.


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The ability to continuously acquire simultaneous EEG and fMRI data during seizures presents a formidable challenge both clinically and technically. Published ictal fMRI reports have so far been unable to benefit from simultaneous electrographic recordings and remain largely assumptive. Unique findings from a Continuous EEG-correlated fMRI experiment are presented in which a focal subclinical seizure was captured in its entirety. For the first time dynamic and biphasic Blood Oxygen Level Dependent (BOLD) signal changes are shown using statistical parametric mapping time-locked to the ictal EEG activity localizing seizure generation and propagation sites, with millimeter resolution, to electroclinically concordant gray matter structures. Though presently of limited clinical applicability, a new avenue is opened for further research


[ Brain mapping ] [ *electroencephalography ] [ Epilepsy/*pathology/*physiopathology ] [ Epilepsy ] [ Tonic-clonic/pathology/physiopathology ] [ Fourier analysis ] [ Human ] [ Image processing ] [ Computer-assisted ] [ *magnetic resonance imaging ] [ Male ] [ Middle aged ] [ Oxygen/blood ] [ Support ] [ Non-u.s. gov't ] [ Telemetry ]


A. Salek-haddadi
M. Merschhemke
L. Lemieux
D. R. Fish

BibTex Reference

   Author = {Salek-Haddadi, A. and Merschhemke, M. and Lemieux, L. and Fish, D. R.},
   Title = {Simultaneous {EEG}-{C}orrelated {I}ctal f{MRI}},
   Journal = {NeuroImage},
   Volume = {16},
   Number = {1},
   Pages = {32--40},
   Year = {2002}

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