Jump to : Download | Abstract | Keywords | Contact | BibTex reference | EndNote reference |


E. Salli, A. Korvenoja, A. Visa, T. Katila, H. J. Aronen. Reproducibility of fMRI: effect of the use of contextual information. NeuroImage, 13(3):459-471, 2001.


Download paper: (link)

Copyright notice:This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. These works may not be reposted without the explicit permission of the copyright holder.


We studied the effect of use of contextual information on the reproducibility of the results in analysis of fMRI data. We used data from a repeated simple motor fMRI experiment. In the first approach, statistical parametric maps were computed from a spatially unsmoothed data and thresholded using a Bonferroni corrected threshold. In the second approach, the maps were computed from a spatially unsmoothed data but were segmented into nonactive and active regions using a spatial contextual clustering method. In the third approach, the statistical parametric maps were computed from spatially smoothed data and thresholded, using, optionally, a spatial extent threshold. The variation in the classification was largest in the Bonferroni thresholded statistical parametric maps. There were no significant differences in variation between statistical parametric maps generated with all the other methods. In addition to reproducibility, the detection rates of weak simulated activations in the presence of measured scanner and physiological noise were investigated. Contextual clustering method was the most sensitive method, while the least sensitive method was the Bonferroni corrected thresholding. Using simulated data, we demonstrated that the contextual clustering method preserves the shapes of activation regions better than the method using spatial smoothing of the data


[ Adult ] [ Attention/*physiology ] [ *brain mapping ] [ Cerebral cortex/*physiology ] [ Cluster analysis ] [ Comparative study ] [ Echo-planar imaging ] [ Human ] [ *image processing ] [ Computer-assisted ] [ *magnetic resonance imaging ] [ Motor activity/*physiology ] [ Pattern recognition ] [ Visual ] [ Phantoms ] [ Imaging ] [ Sensitivity and specificity ] [ Support ] [ Non-u.s. gov't ]


E. Salli
A. Korvenoja
A. Visa
T. Katila
H. J. Aronen

BibTex Reference

   Author = {Salli, E. and Korvenoja, A. and Visa, A. and Katila, T. and Aronen, H. J.},
   Title = {Reproducibility of f{MRI}: effect of the use of contextual information},
   Journal = {NeuroImage},
   Volume = {13},
   Number = {3},
   Pages = {459--471},
   Year = {2001}

EndNote Reference [help]

Get EndNote Reference (.ref)