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O. J. Arthurs, S. Boniface. How well do we understand the neural origins of the fMRI BOLD signal?. Trends Neurosci, 25(1):27-31, 2002.


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The successful use of functional magnetic resonance imaging (fMRI) as a way of visualizing cortical function depends largely on the important relationships between the signal observed and the underlying neuronal activity that it is believed to represent. Currently, a relatively direct correlation seems to be favoured between fMRI signals and population synaptic activity (including inhibitory and excitatory activity), with a secondary and potentially more variable correlation with cellular action potentials


[ Action potentials/physiology ] [ Animals ] [ Cerebral cortex/*physiology ] [ Cerebrovascular circulation/*physiology ] [ Excitatory postsynaptic potentials/physiology ] [ Human ] [ *magnetic resonance imaging ] [ Neural inhibition/physiology ] [ Neurons/*physiology ] [ Support ] [ Non-u.s. gov't ] [ Synaptic transmission/*physiology ]


O. J. Arthurs
S. Boniface

BibTex Reference

   Author = {Arthurs, O. J. and Boniface, S.},
   Title = {How well do we understand the neural origins of the f{MRI} {BOLD} signal?},
   Journal = {Trends Neurosci},
   Volume = {25},
   Number = {1},
   Pages = {27--31},
   Year = {2002}

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